Author

Dhananjay Umrani

Agency for Science, Technology and Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:phylogenetics / evolution· 1 Assay:proteomics· 1

Frequent Co-Authors

Bong Hwa Gan· 1 shared Darren Wan Teck Lim· 1 shared Greg Li· 1 shared Hannes HentzeiD· 1 shared Kantharaj Ethirajulu· 1 shared Lay Hoon Lee· 1 shared Maryam Yasin· 1 shared Pauline Yeo· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Bong Hwa Gan

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1 paper

Recent·Most cited

Pharmacodynamic evaluation of AUM001/tinodasertib, an oral inhibitor of mitogen-activated protein kinase (MAPK)-interacting protein kinase 1, 2 (MNK1/2) in preclinical models and tissues from a Phase 1 clinical study

Bong Hwa Gan, Lay Hoon Lee, Reika Takeda, Maryam Yasin, Vincenzo Teneggi, Kantharaj Ethirajulu, Pauline Yeo, Dhananjay Umrani, Vishal Pendharkar, Darren Wan Teck Lim, Greg Li, Qingshu Lu, Yang Cao, Ranjani Nellore, Stephanie Blanchard, , Veronica Novotny-Diermayr

This paper evaluates the pharmacodynamic effects of AUM001/tinodasertib in preclinical models and human tissues from a Phase 1 study, showing dose-dependent inhibition of eIF4E phosphorylation in tumors and PBMCs.

Journal of Cancer Science and Clinical Therapeutics · Jan 1, 2024Peer-reviewedCancer Biology