Expanded Proteome Coverage Powered by Advanced Ion Processing Enables Deep Single-Cell Drug Response Subtyping in Human Stem Cell Derived Cardiomyocytes
Johannes V. Janssens, Aleksandra Binek, Lizhuo Ai, Ajay Bhardwaj, Madelyn Arzt, Diego Assis, Matthew Willetts, Michael Krawitzky, Daniel Hornburg, Arun Sharma, Aleksandr B. Stotland, Jennifer E. Van Eyk
This paper introduces an enhanced single-cell proteomics workflow using timsUltra AIP, showing improved proteome coverage and drug response subtyping in human iPSC-CMs.
bioRxiv · May 31, 2026 · PreprintMolecular Biology