Stefan Tenzer

The paper introduces mzQC, a standard for representing quality control metrics in mass spectrometry, enabling interoperable and machine-readable QC reporting.

This study investigates the role of PHB2 in T cell proliferation, differentiation, and effector functions, finding that PHB2 deficiency causes cell cycle arrest and metabolic dysfunction.

This study identifies p1/s1, a 3'-nucleotidase/nuclease in Leishmania major, which helps the parasite evade host immune responses by generating adenosine and degrading neutrophil extracellular traps.

This study benchmarks DDA-PASEF immunopeptidomics software tools, showing PEAKS identifies the most immunopeptides, while database size affects performance across platforms.

The paper compares CCR8+ Treg cells in tumor and tumor-free tissues using chromatin accessibility and DNA methylation, finding high similarity suggesting tumor microenvironment activation of tissue Treg cells.

This study identifies IRF4 interactors and their role in regulating context-dependent transcriptional programs in Th17 and Treg cells using ChIP-Seq and proteomics.

MAETi enables immunopeptidome profiling from 1E4 cells with high peptide coverage and SAV epitope detection.

This study identifies PfSET10 as a H3K18 methyltransferase in Plasmodium falciparum that regulates chromatin structure and is essential for intraerythrocytic development.

This paper identifies SV2A as a mitochondrial outer membrane protein that regulates mitochondrial morphology and autophagy through interactions with DRP1 and ATG9A.

TIMS2Rescore is a data-driven rescoring pipeline optimized for DDA-PASEF data that improves protein identification in proteomics analyses.

The paper benchmarks dia-PASEF with timsTOF HT for high-throughput proteome analysis in a multi-center study, showing consistent protein and peptide identification across laboratories.

The paper identifies novel proteins in Plasmodium falciparum gametocyte egress vesicles using imaging and BioID, revealing distinct proteomes for osmiophilic bodies and g-exonemes.

The paper introduces midiaPASEF, a DIA scan mode that enhances information content in proteomics, enabling precise precursor m/z determination and efficient automated processing.

This study identifies how GDAP1 loss of function disrupts actin signaling, leading to mitochondrial tubularity and metabolic changes in CMT4A.

This study shows that loss of EGFL7 enhances memory by increasing VEGF-D, which promotes adult neurogenesis and improves memory consolidation in mice.

This paper demonstrates that locality-sensitive hashing can classify signals in high-throughput mass spectrometry data efficiently and scalably.

This study shows that oligodendrocyte exosome secretion supports axonal transport and neuronal viability, and its impairment leads to axonal degeneration in mouse mutants.