Divya Murali

Predictive in vitro profiling of LNP-induced innate immune response using an iPSC-derived monocyte model

This study develops an iPSC-derived monocyte model to predict LNP-induced innate immune responses, showing improved reproducibility and correlation with in vivo cytokine responses.

Liver transplant rejection features memory cell priming, spatially differentiated networks and novel drug targets.

The paper identifies molecular and spatial features of early liver transplant rejection, including primed T-cells, immune synapse activation, and novel drug targets like proteasomal and HSP90 inhibitors.

The molecular chronology of mammary epithelial cell fate switching

The paper maps the molecular programs enabling basal-to-luminal fate switching in mammary epithelial cells using time-resolved single-cell epigenetic and transcriptomic analyses.