Dong-Mei Chen

Reversal of microRNA-blocked tumor suppressors by biphenyl- dicarboxylate impedes endotoxin-induced hepatic hyperplasia

This study shows BPDC reverses microRNA-mediated suppression of tumor suppressors, reducing hepatic hyperplasia induced by LPS.

Short-hairpin RNA-guided single gene knockdown reverses triple-negative breast cancer

This study uses shRNA to knockdown iNOS and ER in breast cancer cells, showing that reducing iNOS inhibits TNBC growth while reducing ER promotes cancer-like features.