Author

Donna C. Decker

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Carole OberiD· 3 shared Marcelo A. NóbregaiD· 3 shared Nathan SchoettleriD· 3 shared Anne I. SperlingiD· 2 shared Noboru J. SakabeiD· 2 shared Xiaoyuan ZhongiD· 2 shared Cara Lynn Hrusch· 1 shared Chanie L. Howard· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Carole OberORCID

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3 papers

Recent·Most cited

Single-cell multiomic profiling of lung immune cells identifies novel asthma risk genes and cell-type specific functions

Jing Gu, Donna C. Decker, Xiaoyuan Zhong, Anne I. Sperling, Carole Ober, Marcelo A. Nóbrega, Xin He, Nathan Schoettler

The paper uses single-cell multi-omics data to identify asthma risk genes and their cell-type specific functions in lung immune cells.

medRxiv · Feb 9, 2026 · PreprintGenetic & Genomic Medicine

Shared loci but distinct variants underlie genetic architecture of allergic diseases

Isabella M. Salamone, Xiaoyuan Zhong, Noboru J. Sakabe, Robert Mitchell, William Wentworth-Sheilds, Li Zhang, Emma E. Thompson, Donna C. Decker, Clayton H. Rische, Xuanyao Liu, Nathan Schoettler, Carole Ober, Xin He, Marcelo A. Nóbrega

The paper identifies disease-specific risk variants and shared effector genes in allergic diseases using functional fine-mapping and expression quantitative trait loci.

medRxiv · Jun 6, 2025 · PreprintGenetic & Genomic Medicine

Asthma-associated variants induce IL33 differential expression through a novel regulatory region

Ivy Aneas, Donna C. Decker, Chanie L. Howard, Débora R. Sobreira, Noboru J. Sakabe, Kelly M. Blaine, Michelle M. Stein, Cara Lynn Hrusch, Lindsey E. Montefiori, Juan J. Tena, Kevin M. Magnaye, Selene M. Clay, James E. Gern, Daniel J. Jackson, Matthew C. Altman, , Marcelo A. Nóbrega

The paper identifies a regulatory region near the IL33 gene that influences asthma risk through allele-specific expression and OCT-1 binding.

bioRxiv · Sep 9, 2020 · PreprintGenomics