Spatial distribution of private gene mutations in clear cell renal cell carcinoma
A. L. Moore, A. A. Batavia, J. Kuipers, J. Singer, E. Burcklen, P. Schraml, C. Beisel, H. Moch, N. Beerenwinkel
The paper analyzes intra-tumour heterogeneity and subclonal mutations in clear cell renal cell carcinoma using multi-regional sequencing, finding that most tumours harbor private mutations and clonally exclusive pathway pairs.
bioRxiv · Apr 26, 2021 · PreprintCancer Biology