Author

A. L. Moore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

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Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:clustering· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:whole-exome sequencing· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

C. Beisel· 3 shared N. Beerenwinkel· 3 shared H. Moch· 2 shared J. Kuipers· 2 shared P. Schraml· 2 shared A. A. Batavia· 1 shared A. Futreal· 1 shared C. Dimitrakopoulos· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCancer Biology

C. Beisel

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Author profile →

3 papers

Recent·Most cited

A statistical test for clonal exclusivity in tumour evolution

J. Kuipers, A. L. Moore, K. Jahn, P. Schraml, F. Wang, K. Morita, A. Futreal, K. Takahashi, C. Beisel, H. Moch, N. Beerenwinkel

This paper introduces a statistical test, GeneAccord, to identify clonally exclusive gene pairs in tumours and applies it to AML data, finding 6 exclusive and 2 co-occurring pairs.

bioRxiv · May 5, 2021 · PreprintCancer Biology

Spatial distribution of private gene mutations in clear cell renal cell carcinoma

A. L. Moore, A. A. Batavia, J. Kuipers, J. Singer, E. Burcklen, P. Schraml, C. Beisel, H. Moch, N. Beerenwinkel

The paper analyzes intra-tumour heterogeneity and subclonal mutations in clear cell renal cell carcinoma using multi-regional sequencing, finding that most tumours harbor private mutations and clonally exclusive pathway pairs.

bioRxiv · Apr 26, 2021 · PreprintCancer Biology

Dynamic changes of genomic and transcriptomic tumor diversity during melanoma progression

A. L. Moore, C. Dimitrakopoulos, S. Flückiger-Mangual, L. Frischknecht, C. Beisel, W. Krek, N. Beerenwinkel

This study tracks genomic and transcriptomic changes in melanoma progression using a mouse model, identifying key genes and pathways involved in metastasis.

bioRxiv · Mar 18, 2021 · PreprintCancer Biology