PIP2-dependent coupling of voltage sensor and pore domains in Kv7.2
S. Pant, J. Zhang, E. C. Kim, H. J. Chung, E. Tajkhorshid
This study identifies PIP2 binding sites in Kv7.2 channels using simulations and electrophysiology, showing how PIP2 couples voltage sensor and pore domains during activation.
bioRxiv · May 11, 2021Biophysics