The Trichloroethylene Metabolite S-(1,2-dichlorovinyl)-l-cysteine Inhibits Lipopolysaccharide-induced Transcriptomic Inflammation Pathways and Cytokine Secretion in a Macrophage Cell Model
S. M. Harris, K. M. Bakulski, J. Dou, E. Houskamp, E. C. Scheeres, E. Schellenboom, O. Harlow, R. Loch-Caruso, E. Boldenow
This study shows DCVC inhibits LPS-induced inflammation and cytokine secretion in macrophages by downregulating key inflammatory pathways and genes.
bioRxiv · Mar 15, 2022Pharmacology & Toxicology