Pharmacology & ToxicologybioRxiv
The Trichloroethylene Metabolite S-(1,2-dichlorovinyl)-l-cysteine Inhibits Lipopolysaccharide-induced Transcriptomic Inflammation Pathways and Cytokine Secretion in a Macrophage Cell Model
S. M. Harris, K. M. Bakulski, J. Dou…·E. Boldenow
This study shows DCVC inhibits LPS-induced inflammation and cytokine secretion in macrophages by downregulating key inflammatory pathways and genes.
DOI 10.1016/j.tiv.2022.105429