Author

E. Cassella

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

P. D. Bieniasz· 2 shared T. Kueck· 2 shared B. Kim· 1 shared F. Schmidt· 1 shared G. Tekes· 1 shared J. Holler· 1 shared L.-M. Bloyet· 1 shared O. Pornillos· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

P. D. Bieniasz

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2 papers

Recent·Most cited

Vesicular stomatitis virus transcription is inhibited by TRIM69 in the interferon-induced antiviral state

T. Kueck, L.-M. Bloyet, E. Cassella, T. Zang, F. Schmidt, V. Brusic, G. Tekes, O. Pornillos, S. Whelan, P. D. Bieniasz

This study identifies TRIM69 as an IFN-induced antiviral factor that inhibits VSVIND replication by targeting its phosphoprotein P through a novel transcriptional inhibition mechanism.

bioRxiv · Jun 27, 2019Microbiology

The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression

P. D. Bieniasz, T. Kueck, E. Cassella, J. Holler, B. Kim

This study shows that AhR and IFN-gamma activation repress CDK1/2 and cyclins, reducing dNTP levels and inhibiting HIV-1 and HSV-1 replication.

bioRxiv · Jun 22, 2018Immunology