Cirrhosis and Inflammation Regulates CYP3A4 Mediated Chemoresistance in Vascularized Hepatocellular Carcinoma-on-a-chip
A. Ozkan, D. L. Stolley, E. Cressman, M. McMillin, T. Yankeelov, M. N. Rylander
This paper develops a vascularized HCC-on-a-chip model to study how cirrhosis and inflammation affect CYP3A4-mediated chemoresistance and treatment efficacy.
bioRxiv · May 4, 2022 · PreprintBioengineering