Author

M. McMillin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Assay:metabolomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Ozkan· 2 shared A. Sidebottom· 2 shared A. Sundararajan· 2 shared D. L. Stolley· 2 shared D. Moran· 2 shared E. G. Pamer· 2 shared E. Waligurski· 2 shared M. N. Rylander· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioengineering

A. Ozkan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species and strain level diversity and evolution

Z. J. Zhang, C. G. Cole, M. Coyne, H. Lin, N. Dylla, R. C. Smith, E. Waligurski, R. Ramaswamy, C. Woodson, V. Burgo, J. Little, D. Moran, A. Rose, M. McMillin, E. Mcspadden, , L. E. Comstock

The paper characterizes a large collection of Bacteroidales isolates from the human gut, revealing genomic and metabolomic diversity and horizontal gene transfer across species.

bioRxiv · Mar 8, 2024Microbiology

Microbially-catalyzed conjugation of GABA and tyramine to bile acids

M. Mullowney, A. Fiebig, M. Schnizlein, M. McMillin, A. R. Rose, J. Koval, D. Rubin, S. Dalal, M. Sogin, E. Chang, A. Sidebottom, S. Crosson

The paper identifies bacteria that conjugate GABA and tyramine to bile acids in the human gut and shows these conjugates are present in stool and J-pouch contents.

bioRxiv · Sep 25, 2023Microbiology

Dietary- and host-derived metabolites are used by diverse gut bacteria for anaerobic respiration

A. S. Little, I. T. Younker, M. S. Schechter, P. Nol Bernardino, R. Meheust, J. Stemczynski, K. Scorza, M. W. Mullowney, D. Sharan, E. Waligurski, R. Smith, R. Ramanswamy, W. Leiter, D. Moran, M. McMillin, , S. H. Light

The paper identifies gut bacteria that use dietary and host-derived metabolites as electron acceptors in anaerobic respiration, revealing new metabolic pathways and reductase evolution.

bioRxiv · Dec 26, 2022Microbiology

Cirrhosis and Inflammation Regulates CYP3A4 Mediated Chemoresistance in Vascularized Hepatocellular Carcinoma-on-a-chip

A. Ozkan, D. L. Stolley, E. Cressman, M. McMillin, T. Yankeelov, M. N. Rylander

This paper develops a vascularized HCC-on-a-chip model to study how cirrhosis and inflammation affect CYP3A4-mediated chemoresistance and treatment efficacy.

bioRxiv · May 4, 2022 · PreprintBioengineering

Tumor Microenvironment Alters Chemoresistance of Hepatocellular Carcinoma Through CYP3A4 Metabolic Activity

A. Ozkan, D. L. Stolley, E. N. K. Cressman, M. McMillin, S. DeMorrow, T. E. Yankeelov, M. N. Rylander

This study shows that HCC chemoresistance to doxorubicin varies with tumor microenvironment stiffness and oxygen levels, mediated by CYP3A4 expression.

bioRxiv · Jan 23, 2021Cancer Biology