Macromolecular crowding limits growth under pressure
B. Alric, C. Formosa-Dague, E. Dague, L. J. Holt, M. Delarue
The paper shows that growth-induced pressure in confined cells increases macromolecular crowding, which hinders protein expression and reduces growth, without requiring specific molecular sensors.
bioRxiv · Jun 4, 2021Biophysics