Author

E. Fonseca

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Varela-Vazquez· 2 shared J. R. Caeiro· 2 shared M. D. Mayan· 2 shared M. Varela-Eirin· 2 shared A. Blanco· 1 shared A. Calanas-Continente· 1 shared A. Carneiro-Figueira· 1 shared A. Casado-Diaz· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

A. Varela-Vazquez

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cx43 Enhances Response to BRAF/MEK Inhibitors by Reducing DNA Repair Capacity

A. Varela-Vazquez, A. Guitian-Caamano, P. Carpintero-Fernandez, V. Alvarez, A. Carneiro-Figueira, M. Varela-Eirin, T. Calleja-Chucla, S. Bravo, A. Vidal, J. Sendon-Lago, M. Rodriguez-Candela Mateos, J. R. Caeiro, M. G. Blanco, G. Sabio, C. Rivas, , M. D. Mayan

This study shows that Cx43 enhances the effectiveness of BRAF/MEKi by reducing DNA repair, leading to increased DNA damage and cellular senescence, and proposes a novel therapeutic approach using sEVs.

bioRxiv · Jul 15, 2024Cancer Biology

Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and cartilage regeneration in osteoarthritis

M. Varela-Eirin, A. Varela-Vazquez, C. L. Paino, A. Casado-Diaz, A. Calanas-Continente, V. Mato, E. Fonseca, M. Kandouz, A. Blanco, J. R. Caeiro, M. D. Mayan

This study shows that olive-derived polyphenols like oleuropein target Cx43 and senescence in osteoarthritis cells, promoting cartilage regeneration and reducing inflammation.

bioRxiv · Jun 28, 2019 · PreprintCell Biology