Chemoprophylaxis vaccination with a Plasmodium liver stage autophagy mutant affords enhanced and long-lasting protection
I. Coppens, T. Sahu, E. Gehrke, Y. Flores Garcia, G. Mlambo, J. Romano
This paper shows that a Plasmodium liver stage mutant vaccine under chemoprophylaxis regimen provides superior long-lasting protection compared to wild-type sporozoites in mice.
bioRxiv · Oct 23, 2020Immunology