Post-translational Modification of α-Synuclein Modifies Monomer Dynamics and Aggregation Kinetics
K. Gamage, B. Wang, E. Hard, T. Van, A. Galesic, G. Phillips, M. R. Pratt, L. Lapidus
This study examines how O-GlcNAcylation at T72 and S87 of α-synuclein affects its monomer dynamics and aggregation kinetics, revealing differential impacts on protein behavior.
bioRxiv · May 6, 2024 · PreprintBiophysics