Glioma-associated tertiary lymphoid structures are sites of lymphocyte clonal expansion and plasma cell formation
P. Cakmak, J. H. Lun, A. Singh, J. Macas, J. Schupp, M. Koehler, T. Starzetz, M. C. Burger, E. Steidl, L. M. Hasse, E. Hattingen, K. H. Plate, Y. Reiss, K. Imkeller
The paper identifies tertiary lymphoid structures in gliomas as sites of immune response, showing they correlate with better survival and involve T and B cell clonal expansion and plasma cell formation.
bioRxiv · Jul 4, 2024Immunology