Author

E. Hegedus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

G. Mocsar· 2 shared A. Csoti· 1 shared A. Schamberger· 1 shared B. Scholtz· 1 shared D. Tremethick· 1 shared E. Csosz· 1 shared E. F. Niaki· 1 shared G. Mezo· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

G. Mocsar

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Author profile →

2 papers

Recent·Most cited

Nucleotide binding is the critical regulator of ABCG2 conformational transitions

Z. Gyöngy, G. Mocsar, E. Hegedus, T. Stockner, Z. Ritter, L. Homolya, A. Schamberger, T. I. Orban, J. Remenyik, G. Szakacs, K. Goda

This study investigates how nucleotide binding regulates conformational transitions in ABCG2, showing it induces the inward-to-outward facing switch and interacts with substrate binding.

bioRxiv · Oct 19, 2022Biochemistry

EPIGENETIC MODULATION VIA THE C-TERMINAL TAIL OF H2A.Z

L. Imre, P. Nanasi, I. Benhamza, K. N. Enyedi, G. Mocsar, R. Bosire, E. Hegedus, E. F. Niaki, A. Csoti, Z. Darula, E. Csosz, S. Poliska, B. Scholtz, G. Mezo, Z. Bacso, , G. Szabo

The paper shows that the C-terminal tail of H2A.Z affects nucleosome stability and chromatin structure, with targeted peptides altering gene expression and chromatin sensitivity.

bioRxiv · Feb 22, 2021Cell Biology