Schlafen family member 5 (SLFN5) regulates LAT1-mediated mTOR activation in castration-resistant prostate cancer
R. S. Martinez, M. J. Salji, L. Rushworth, C. Ntala, G. Rodriguez Blanco, A. Hedley, W. Clark, P. Peixoto, E. Hervouet, E. Renaude, S. H. Kung, L. C. Galbraith, C. Nixon, S. Lilla, G. M. MacKay, , H. Y. Leung
This study identifies SLFN5 as an AR-regulated biomarker in CRPC that promotes tumour growth by regulating LAT1-mediated mTOR activation.
bioRxiv · Sep 17, 2020 · PreprintCancer Biology