Author

E. J. Schaefer

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Apffel· 1 shared C. A. Meyer· 1 shared C. J. Gibson· 1 shared E. R. Adelman· 1 shared E. S. Wang· 1 shared E. S. Winer· 1 shared H. M. Murdock· 1 shared H. W. Long· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Apffel

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1 paper

Recent·Most cited

BCOR and BCORL1 mutations disrupt PRC1.1 repressive function in leukemia by unlinking the RING-PCGF1 enzymatic core from target genes

E. J. Schaefer, W. C. Wang, C. A. Meyer, P. Cejas, M. D. Gearhart, E. R. Adelman, I. Fares, A. Apffel, K. Lim, Y. Xie, C. J. Gibson, M. Schenone, H. M. Murdock, E. S. Wang, L. P. Gondek, , R. C. Lindsley

This study shows BCOR and BCORL1 mutations disrupt PRC1.1 function in leukemia by separating its enzymatic core from chromatin targets, leading to treatment resistance.

bioRxiv · Mar 8, 2021 · PreprintCancer Biology