Human saphenous vein provides a unique source of anti-calcific pericytes for prosthetic cardiac valve engineering
E. Jover, M. Fagnano, W. Cathery, S. Slater, E. Pisanu, Y. Gu, E. Avolio, D. Bruno, D. Baz-Lopez, A. Faulkner, M. Carrabba, P. Madeddu
This study identifies human adventitial pericytes from saphenous vein as anti-calcific cells for prosthetic cardiac valve engineering, showing resistance to osteochondrogenic induction via miR-132 regulation.
bioRxiv · Jul 14, 2020 · PreprintCell Biology