The SPIRE1 actin nucleator coordinates actin/myosin functions in the regulation of mitochondrial motility
F. Straub, T. Welz, H. Alberico, R. O. Brandao, A. Huber, A. Samol-Wolf, C. Brakebusch, D. Woods, M. Kollmar, J. Martin-Gonzalez, E. Kerkhoff
This study shows that SPIRE1 regulates mitochondrial motility by targeting myosin 5 and formin to mitochondria, inhibiting their movement.
bioRxiv · Jun 19, 2020 · PreprintCell Biology