A novel drug-combination screen in zebrafish identifies epigenetic small molecule candidates for Duchenne muscular dystrophy
G. H. Farr, M. Morris, A. Gomez, T. Pham, E. U. Parker, E. Kilroy, S. Said, C. Henry, L. Maves
The paper identifies two epigenetic small molecules, oxamflatin and salermide, that improve skeletal muscle structure in zebrafish models of Duchenne muscular dystrophy through a drug-combination screen.
bioRxiv · Feb 19, 2020Pharmacology & Toxicology