CDK activity at the centrosome regulates the cell cycle
E. L. Roberts, N. Kapadia, T. Auchynnikava, S. Basu, P. Nurse
This study shows that the hydrophobic patch mediates cyclin-CDK localization to the centrosome, which is essential for mitotic entry and CDK substrate phosphorylation.
bioRxiv · Aug 16, 2023Cell Biology