Low-pathogenic virus induced immunity against TBEV protects mice from disease but not from virus entry into the CNS
M. Petry, M. Palus, E. Leitzen, J. G. Mitterreiter, B. Huang, A. Kröger, G. M. G. M. Verjans, W. Baumgärtner, G. F. Rimmelzwaan, D. Ruzek, A. Osterhaus, C. Prajeeth
This study shows that pre-infection with low-virulent or avirulent TBEV strains protects mice from lethal TBEV-Hypr infection but allows virus entry into the CNS.
bioRxiv · Jan 11, 2021 · PreprintImmunology