Disordered peptides impair neutrophil bacterial clearance and enhance tissue damage in septic patients
C. I. Timar, F. Kolonics, V. Berzsenyi, E. Tamaska, A. Parkanyi, M. L. Merchant, D. W. Wilkey, Z. Ivanyi, K. R. McLeish, E. Ligeti
The paper shows that disordered peptides in septic patients' plasma impair neutrophil function and increase tissue damage by altering ROS production and bacterial clearance.
bioRxiv · Jul 31, 2020 · PreprintImmunology