Author

E. Ly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:Arabidopsis· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

J. Goodrich· 2 shared J. Kugel· 2 shared A. A. C. Hooft van Huysduynen· 1 shared A. E. Powell· 1 shared A. Forrest· 1 shared A. Franzke· 1 shared A. Guggisberg· 1 shared A. Harkess· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

J. Goodrich

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Global Phylogeny of the Brassicaceae Provides Important Insights into Gene Discordance

K. P. Hendriks, C. Kiefer, I. A. Al-Shehbaz, C. D. Bailey, A. A. C. Hooft van Huysduynen, L. Nikolov, L. Nauheimer, A. R. Zuntini, D. A. German, A. Franzke, M. A. Koch, M. A. Lysak, O. Toro-Nunez, B. Ozudogru, V. R. Invernon, , Fore

This paper presents a comprehensive Brassicaceae phylogeny, identifies cytonuclear discordance due to hybridization, and proposes new tribes, providing a tool for biodiversity and plant biology studies.

bioRxiv · Sep 1, 2022Evolutionary Biology

Single molecule studies characterize the kinetic mechanism of tetrameric p53 binding to different native response elements

J. P. Suwita, C. K. Voong, E. Ly, J. A. Goodrich, J. F. Kugel

This study uses single molecule fluorescence to analyze p53 tetramer binding dynamics to five native response elements, revealing two kinetically distinct populations and sequence-dependent dissociation rates.

bioRxiv · Jun 1, 2022Biochemistry

Single molecule studies reveal that p53 tetramers dynamically bind response elements containing one or two half sites

E. Ly, J. Kugel, J. Goodrich

This study uses single molecule fluorescence to show p53 tetramers bind DNA response elements with varying half-site configurations, revealing kinetic stability depends on half-site number and phasing.

bioRxiv · Dec 19, 2019Biochemistry

Release of human TFIIB from actively transcribing complexes is triggered upon synthesis of 7 nt and 9 nt RNAs

E. Ly, A. E. Powell, J. Goodrich, J. Kugel

The paper investigates TFIIB release during transcription using a single molecule fluorescence system and finds it occurs at two points with similar kinetics, supporting its role in maintaining Pol II activity during transition to elongation.

bioRxiv · Dec 19, 2019Biochemistry