LRP1 Triggers Pro-inflammatory Cell-signaling in Response to Extracellular Tau Independently of the NMDA Receptor
P. Azmoon, E. Mantuano, B. Poudel, C. Zampieri, S. L. Gonias
This paper shows that extracellular Tau activates pro-inflammatory signaling via LRP1 in macrophages, microglia, and astrocytes, independent of the NMDA receptor.
bioRxiv · Oct 6, 2023 · PreprintCell Biology