Author

B. Poudel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1

Frequent Co-Authors

P. Gurung· 2 shared A. J. Borst· 1 shared A. McGuire· 1 shared A. Wall· 1 shared B. Fiala· 1 shared B. L. Stoddard· 1 shared C. Correnti· 1 shared C. Marques-da-Silva· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

P. Gurung

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Author profile →

4 papers

Recent·Most cited

LRP1 Triggers Pro-inflammatory Cell-signaling in Response to Extracellular Tau Independently of the NMDA Receptor

P. Azmoon, E. Mantuano, B. Poudel, C. Zampieri, S. L. Gonias

This paper shows that extracellular Tau activates pro-inflammatory signaling via LRP1 in macrophages, microglia, and astrocytes, independent of the NMDA receptor.

bioRxiv · Oct 6, 2023 · PreprintCell Biology

Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge

H. Malhi, L. J. Homad, Y.-H. Wan, B. Poudel, B. Fiala, A. J. Borst, J. Y. Wang, C. Walkey, J. Price, A. Wall, S. Singh, Z. Moodie, S. Handa, C. Correnti, B. L. Stoddard, , A. McGuire

This study evaluates a nanoparticle vaccine displaying EBV gH/gL, showing it protects humanized mice against lethal EBV challenge, while monomeric gH/gL does not.

bioRxiv · Feb 17, 2022Immunology

Altered cleavage of Caspase-1 in hepatocytes limits control of malaria in the liver

C. Marques-da-Silva, B. Poudel, R. P. Baptista, K. Peissig, L. S. Hancox, J. C. Shiau, L. Pewe, M. J. Shears, T.-D. Kanneganti, P. Sinnis, D. E. Kyle, P. Gurung, J. T. Harty, S. P. Kurup

This study shows that limited Caspase-1 cleavage in hepatocytes reduces pyroptosis and cytokine maturation, impairing malaria control, and that enhancing ASC expression improves immune response.

bioRxiv · Jan 28, 2021 · PreprintImmunology

Leishmania major degrades murine CXCL1 - an immune evasion strategy

M. S. Yorek, B. Poudel, L. Mazgaeen, R. M. Pope, M. E. Wilson, P. Gurung

This study identifies that Leishmania major degrades murine CXCL1 via metalloproteases, impairing neutrophil recruitment and highlighting a potential therapeutic target for immune evasion.

bioRxiv · Mar 11, 2019Microbiology