Author

E. McClure

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1

Frequent Co-Authors

J. G. Scott· 3 shared A. Durmaz· 2 shared M. Hitomi· 2 shared A. Dhawan· 1 shared A. Kaznatcheev· 1 shared A. Marusyk· 1 shared D. Crozier· 1 shared D. F. K. Williamson· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBioengineering

J. G. Scott

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Author profile →

3 papers

Recent·Most cited

A low-cost, open-source evolutionary bioreactor and its educational use

V. Gopalakrishnan, D. Crozier, K. Card, L. Chick, N. P. Krishnan, E. McClure, J. Pelesko, D. F. K. Williamson, D. Nichol, S. Mandal, R. A. Bonomo, J. G. Scott

The paper introduces a low-cost, open-source morbidostat for educational use, validated through bacterial resistance experiments and student engagement.

bioRxiv · Sep 1, 2022Bioengineering

Measuring competitive exclusion in non-small cell lung cancer

N. Farrokhian, J. Maltas, M. Dinh, A. Durmaz, P. Ellsworth, M. Hitomi, E. McClure, A. Marusyk, A. Kaznatcheev, J. G. Scott

This study measures frequency-dependent interactions between gefitinib-resistant and sensitive NSCLC populations to show that competitive exclusion depends on growth rate data, not just cost of resistance.

bioRxiv · Sep 18, 2020Cancer Biology

Identifying states of collateral sensitivity during the evolution of therapeutic resistance in Ewings sarcoma

J. A. Scarborough, E. McClure, P. Anderson, A. Dhawan, A. Durmaz, S. L. Lessnick, M. Hitomi, J. G. Scott

This study maps the temporal evolution of collateral sensitivity and resistance in Ewings sarcoma, showing unpredictable patterns in drug response and highlighting transcriptomic changes associated with these states.

bioRxiv · Feb 11, 2020Evolutionary Biology