Centrosome Amplification promotes cell invasion via cell-cell contact disruption and Rap-1 activation
A. Prakash, S. Paunikar, M. Webber, E. McDermott, S. H. Vellanki, K. Thompson, P. Dockery, H. Jahns, J. A. L. Brown, A. M. Hopkins, E. Bourke
This study shows centrosome amplification induces tumourigenic changes in normal breast cells via Rap-1 activation and cell-cell contact disruption.
bioRxiv · May 9, 2022Cell Biology