M. Webber

Collateral sensitivity increases the efficacy of a rationally designed bacteriophage combination to control Salmonella enterica

This study identifies host susceptibility and resistance factors for Salmonella enterica infected by bacteriophages SPLA1a and SPLA5b, showing that their combination reduces phage resistance emergence.

PERK-mediated induction of miR-5p and miR-3p arms of miR-616 regulates cell growth by targeting c-MYC

The paper shows that PERK-mediated induction of miR-5p and miR-3p arms of miR-616 regulates cell growth by targeting c-MYC, with miR-616 expression linked to survival outcomes in breast cancer.

Centrosome Amplification promotes cell invasion via cell-cell contact disruption and Rap-1 activation

This study shows centrosome amplification induces tumourigenic changes in normal breast cells via Rap-1 activation and cell-cell contact disruption.

Antibiotics select for novel pathways of resistance in biofilms

This study shows biofilms of Salmonella Typhimurium rapidly evolve resistance to antibiotics through novel mechanisms, with fitness costs associated with adaptation.

A new massively-parallel transposon mutagenesis approach comparing multiple datasets identifies novel mechanisms of action and resistance to triclosan

This paper introduces a new TraDIS approach with AlbaTraDIS tool to analyze triclosan resistance mechanisms across multiple concentrations, identifying novel genes involved in bacterial survival.

Different impacts of naturally occurring variants of the globally disseminated carbapenemase-encoding plasmid pKpQIL on the biology of host strains

This study compares the host range and fitness impacts of two variants of the pKpQIL plasmid in different bacterial hosts.