Humanized CAR T cells targeting p95HER2
M. Roman, I. Rius Ruiz, A. Grinyo-Escuer, S. Duro-Sanchez, M. Escorihuela, E. Moessner, C. Klein, J. Arribas
This study develops CAR T cells targeting p95HER2, a tumor-specific antigen, showing efficacy against HER2-amplified tumors and metastases with reduced off-tumor effects.
bioRxiv · May 20, 2022 · PreprintCancer Biology