Id4 eliminates the pro-activation factor Ascl1 to maintain quiescence of adult hippocampal stem cells
I. M. Blomfield, B. Rocamonde, M. D. M. Masdeu, E. Mulugeta, S. Vaga, D. L. C. van den Berg, E. Huillard, F. Guillemot, N. Urban
This study shows that Id4 suppresses Ascl1 activity to maintain quiescence of adult hippocampal stem cells by promoting Ascl1 degradation.
bioRxiv · Sep 25, 2018Cell Biology