The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms
D. L. H. Bui, A. Roach, J. Li, S. J. Bandekar, E. Orput, R. Raghavan, D. Arac, R. Sando
This study investigates how different adhesion GPCRs, CELSR1-3 and LPHN3, engage G proteins through distinct activation mechanisms, revealing that cleavage is not universal among aGPCRs.
bioRxiv · Apr 2, 2023 · PreprintCell Biology