Dysregulation of Sterol Regulatory Element-Binding Protein 2 Gene in HIV Treatment-Experienced Individuals
A. Sopeyin, L. Zhou, M. Li, L. Barakat, E. Paintsil
The paper examines how antiretroviral therapy affects cholesterol biosynthesis in HIV-positive individuals, finding upregulated HMGCR and ABCA1 expression and dysregulation in SREBP-2 and LDLR pathways.
bioRxiv · Aug 21, 2019Pharmacology & Toxicology