Somatostatin, an In Vivo Binder to Aβ Oligomers, Binds to βPFOAβ(1-42) Tetramer
E. Puig, J. Tolchard, A. Riera, N. Carulla
This study shows that somatostatin binds specifically to the βPFOAβ(1-42) tetramer but not monomeric Aβ(1-42), providing insights into its role in the amyloid cascade and AD.
bioRxiv · May 11, 2020Biophysics