PI3K inhibition as a novel therapeutic strategy for neoadjuvant chemoradiotherapy resistant oesophageal adenocarcinoma
S. D. Edge, I. Renard, E. Pyne, H. Moody, R. Roy, A. W. Beavis, S. J. Archibald, C. J. Cawthorne, S. G. Maher, I. M. Pires
This study shows that PI3K inhibition improves radiation response in oesophageal adenocarcinoma patients resistant to neo-CRT by upregulating PTEN through miR-187.
The British Journal of Radiology · Mar 1, 2021Peer-reviewedCancer Biology