Author

E. R. Lucas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4 Ecology· 3 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Approach:experimental assay· 4 Organism:Drosophila· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

M. J. Donnelly· 7 shared D. Weetman· 5 shared A. Miles· 3 shared C. S. Clarkson· 3 shared E. Ochomo· 2 shared E. Z. Manzambi· 2 shared J. Midega· 2 shared L. S. Djogbenou· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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7 shared papersEvolutionary Biology

M. J. Donnelly

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Author profile →

8 papers

Recent·Most cited

Cryptic population structure and insecticide resistance in Anopheles gambiae from the southern Democratic Republic of Congo

T. P. W. Dennis, P. Pescod, S. Barasa, L. T. Cerdeira, E. R. Lucas, C. S. Clarkson, A. Miles, A. Asidi, E. Z. Manzambi, E. Metelo, J. Zanga, S. N. Salambi, S. R. Irish, M. J. Donnelly, D. Weetman, F. W. Tezzo

The paper investigates insecticide resistance and population structure in Anopheles gambiae from southern DRC, finding high resistance and genetic differentiation between populations.

bioRxiv · Mar 12, 2024 · PreprintEvolutionary Biology

Parallel evolution in mosquito vectors - a duplicated esterase locus is associated with resistance to pirimiphos-methyl in An. gambiae

S. C. Nagi, E. R. Lucas, A. Egyir-Yawson, J. Essandoh, S. Dadzie, J. Chabi, L. S. Djogbenou, A. A. Medjigbodo, C. V. Edi, G. Ketoh, B. G. Koudou, F. Ashraf, C. S. Clarkson, A. Miles, D. Weetman, M. J. Donnelly

This study identifies a duplicated esterase locus associated with pirimiphos-methyl resistance in Anopheles gambiae through population genomic analysis.

bioRxiv · Feb 1, 2024 · PreprintEvolutionary Biology

Spatially explicit sampling frameworks to identify regions of increased mosquito abundance

B. Kemei, E. Ochomo, M. Ombok, J. Midega, E. R. Lucas, M. J. Donnelly, L. Sedda, D. P. McDermott

This study applies a spatially explicit sampling framework in coastal Kenya to identify high mosquito abundance areas and improve vector control strategies.

bioRxiv · Nov 21, 2023 · PreprintEcology

A gene expression panel for estimating age in males and females of the sleeping sickness vector Glossina morsitans

E. R. Lucas, A. C. Darby, S. J. Torr, M. J. Donnelly

The paper develops a gene expression panel to estimate age in tsetse flies, achieving accurate predictions with minimal gene markers.

bioRxiv · May 12, 2021Ecology

Identification of a rapidly-spreading triple mutant for high-level metabolic insecticide resistance in Anopheles gambiae provides a real-time molecular diagnostic for anti-malarial intervention deployment.

H. Njoroge, A. van't Hof, A. Oruni, D. Pipini, S. C. Nagi, A. Lynd, E. R. Lucas, S. Tomlinson, X. Grau-Bove, D. McDermott, F. t. Wat'senga, E. Z. Manzambi, F. R. Agossa, A. Mokuba, S. R. Irish, , M. J. Donnelly

The paper identifies a triple mutant in Anopheles gambiae associated with pyrethroid resistance and proposes it as a diagnostic for guiding anti-malarial intervention strategies.

bioRxiv · Feb 11, 2021 · PreprintEvolutionary Biology

Apparent negative density-dependent dispersal in tsetse (Glossina spp) is an artefact of inappropriate analysis

J. W. Hargrove, J. Van Sickle, G. A. Vale, E. R. Lucas

The paper shows that apparent negative density-dependent dispersal in tsetse flies is an artifact of flawed analysis, not a real biological phenomenon.

bioRxiv · Dec 17, 2020Zoology

Improved spatial ecological sampling using open data and standardization: an example from malaria mosquito surveillance

L. Sedda, E. R. Lucas, L. S. Djogbenou, A. V. C. Edi, A. Egyr-Yawson, B. I. Kabula, J. Midega, E. Ochomo, D. Weetman, M. J. Donnelly

The paper proposes a framework for ecological sampling design using open data to improve malaria mosquito surveillance by balancing prediction accuracy and sample efficiency.

bioRxiv · Nov 9, 2018Ecology

Whole genome sequencing reveals high complexity of copy number variation at insecticide resistance loci in malaria mosquitoes

E. R. Lucas, A. Miles, N. J. Harding, C. S. Clarkson, M. K. N. Lawniczak, D. P. Kwiatkowski, D. Weetman, M. J. Donnelly, The Anopheles gambiae 1000 Genomes Consortium

The paper uses whole-genome sequencing to identify copy number variations (CNVs) in Anopheles gambiae linked to insecticide resistance, finding CNVs enriched for resistance-related genes and under positive selection.

bioRxiv · Aug 25, 2018Evolutionary Biology