Drag-induced directionality switching of kinesin-5 Cin8 revealed by cluster-motility analysis
H. Handey, E. Reithmann, A. Goldstein-Levitin, J. Al-Bassam, E. Frey, L. Gheber
This study reveals that directionality switching of kinesin-5 Cin8 motors is caused by an asymmetric response to drag forces, identified through cluster-motility analysis and biophysical modeling.
Science Advances · Feb 5, 2021Peer-reviewedBiophysics