Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome
L. Shaashua, A. Eckerling, B. Israeli, G. Yanovich, E. Rosenne, S. Fichman-Horn, I. Ben Zvi, L. Sorski, R. Satchi-Fainaro, T. Geiger, E. K. Sloan, S. Ben-Eliyahu
This study shows that removing a primary tumor can cause small metastases to regress, but not larger ones, and identifies tumor-secreted factors that promote early metastatic growth.
bioRxiv · Mar 12, 2020Cancer Biology