Inhibition and down regulation of the serotonin transporter contribute to the progression of degenerative mitral regurgitation
R. J. Levy, E. Fitzpatrick, E. Castillero, , H. J. Shukla, , V. V. Inamdar, A. E. Aghali, J. B. Grau, N. Rioux, E. Salvati, S. J. Keeney, I. Nissim, R. C. C. Gorman, L. Rauova, S. J. Stachelek, C. R. Brown, , G. Ferrari
This study investigates how inhibition and downregulation of the serotonin transporter (SLC6A4) contribute to the progression of degenerative mitral regurgitation through enhanced HTR2B signaling.
bioRxiv · Mar 10, 2020 · PreprintPhysiology