Author

E. Saridakis

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Baldwin· 1 shared C. Redfield· 1 shared D. A. I. Mavridou· 1 shared D. Gonzalez· 1 shared L. S. Stelzl· 1 shared M. Sansom· 1 shared S. J. Ferguson· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Baldwin

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1 paper

Recent·Most cited

Local frustration determines loop opening during the catalytic cycle of an oxidoreductase

L. S. Stelzl, D. A. I. Mavridou, E. Saridakis, D. Gonzalez, A. Baldwin, S. J. Ferguson, M. Sansom, C. Redfield

This study shows how oxidation of cysteine thiols to a disulfide bond in DsbD introduces local frustration, disrupting the cap-loop structure and enabling loop opening during its catalytic cycle.

bioRxiv · Jun 14, 2020Biophysics