E. Shihabeddin

Trafficking of Connexin36 (Cx36) in the early secretory pathway

This study identifies the C-terminal region of Cx36 as critical for its transport from the ER to the Golgi via interactions with COPII and Grasp55.

Intralumenal docking of Cx36 channels in the ER isolates mis-trafficked protein

The paper investigates how a dysfunctional PDZ binding motif in Cx36 affects its ER export and leads to ER retention and vesicle formation.