V. Liss

Intralumenal docking of Cx36 channels in the ER isolates mis-trafficked protein

The paper investigates how a dysfunctional PDZ binding motif in Cx36 affects its ER export and leads to ER retention and vesicle formation.

Single molecule analyses of Salmonella translocated effector proteins reveal targeting to and dynamics in host cell endomembranes

The paper uses single molecule analysis to study how Salmonella effector proteins reach and interact with host cell endomembranes, revealing dynamics and mechanisms of membrane remodeling.

Single cell analyses reveal distinct adaptation of typhoidal and non-typhoidal Salmonella enterica serovars to intracellular lifestyle

This study compares the intracellular behavior of typhoidal and non-typhoidal Salmonella using single-cell analyses, revealing differences in SPI2-T3SS activity and protein biosynthesis.

A trafficome-wide RNAi screen reveals deployment of early and late secretory host proteins and the entire late endo-/lysosomal vesicle fusion machinery by intracellular Salmonella

This study identifies host factors involved in Salmonella-induced endosomal remodeling through an RNAi screen, revealing key roles for SNARE complexes, GTPases, and clathrin-coated structures.

Blocks in tricarboxylic acid cycle of Salmonella enterica cause global perturbation of carbon storage, motility and host-pathogen-interaction

This study shows that fumarase deficiency in Salmonella enterica disrupts carbon metabolism, leading to glycogen accumulation, altered motility, and increased macrophage phagocytosis.