ANKRD31 regulates spatiotemporal patterning of meiotic recombination initiation and ensures recombination between heterologous sex chromosomes in mice
F. Papanikos, J. A. J. Clement, E. Testa, R. Ravindranathan, C. Grey, I. Dereli, A. Bondarieva, S. Valerio-Cabrera, M. Stanzione, A. Schleiffer, P. Jansa, D. Lustyk, F. Jifeng, J. Forejt, M. Barchi, , A. Toth
This study identifies ANKRD31 as essential for meiotic recombination timing and spatial organization, particularly in sex chromosomes, leading to segregation failure in its absence.
bioRxiv · Sep 28, 2018Cell Biology