A genetic compensatory mechanism regulated by c-Jun and Mef2d modulates the expression of distinct class IIa HDACs to ensure peripheral nerve myelination and repair
H. Cabedo, S. Velasco-Aviles, N. Patel, A. Casillas-Bajo, L. Frutos-Rincon, E. Velasco-Serna, J. Gallar, P. Arthur-Farraj, J. A. Gomez-Sanchez
The paper identifies a genetic compensatory mechanism in Schwann cells involving c-Jun and Mef2d that modulates class IIa HDAC expression to support peripheral nerve myelination and repair.
bioRxiv · Sep 20, 2021Cell Biology