Author

E. W. Lim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

C. M. Metallo· 3 shared M. K. Handzlik· 2 shared A. E. Thalacker-Mercer· 1 shared A. K. Rudd· 1 shared B. D. Cosgrove· 1 shared B. J. Gheller· 1 shared E. L. Bender· 1 shared E. Trefts· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

C. M. Metallo

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Author profile →

3 papers

Recent·Most cited

Metabolic adaptation to progressive mitochondrial dysfunction in aging POLGD257A mice

E. W. Lim, M. K. Handzlik, E. Trefts, J. M. Gengatharan, R. J. Shaw, C. M. Metallo

This study examines metabolic changes in aging PolgD257A mice, revealing altered glycolysis, urea cycle dysfunction, and lipidome shifts linked to neuropathy.

bioRxiv · Apr 29, 2021Biochemistry

A Small Molecule Fluorogenic Probe for the Detection of Sphingosine in Living Cells

A. K. Rudd, N. Mittal, E. W. Lim, C. M. Metallo, N. K. Devaraj

This paper develops a fluorescent probe to detect sphingosine in living cells and demonstrates its use in detecting sphingosine accumulation in NPC1 patient cells.

bioRxiv · Jun 27, 2020Biochemistry

Serine and glycine are essential for human muscle progenitor cell population expansion

B. J. Gheller, J. E. Blum, E. L. Bender, M. E. Gheller, E. W. Lim, M. K. Handzlik, P. J. Stover, M. S. Field, B. D. Cosgrove, C. M. Metallo, A. E. Thalacker-Mercer

This study identifies serine and glycine as essential for human muscle progenitor cell proliferation and shows their availability declines with age, impairing muscle regeneration.

bioRxiv · Nov 7, 2019 · PreprintCell Biology